human hemoglobin genes

human hemoglobin genes
Гены гемоглобина человека — гены, кодирующие разные виды гемоглобина (см. Гемоглобин) человека. Локализованы в хромосомах 11 и 16. Хромосома 11 содержит ген ε-цепочки, 2 гена γ-цепочки Gγ и Aγ, ген δ-цепочки и ген β-цепочки. Хромосома 16 содержит 2 гена ζ цепочки (ζ1 и ζ2) и 2 гена α-цепочки (α2 и α12). Между ζ1 и α2 находится нефункционирующий сегмент ДНК, который на 75% сходен с α2-геном по последовательностям нуклеотидов. Он называется псевдогеном ψa2. Предполагается, что эти родственные гены (Gγ, Aγ; δ, β; ζ2, ζ1; α2, α1) возникли в процессе эволюции в результате дупликаций, то же, конечно, применимо по отношению к гену ψa2.

Англо-русский толковый словарь генетических терминов. — М.: Изд-во ВНИРО. . 1995.

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